If not yet done, copy the distribution network_drive directory to the H: network drive.

Edit H:\CBSU\clusters. This directory contains text files, each file corresponds to a cluster and lists all its nodes.

Copy your BLAST databases to the appropriate H:\CBSU subdirectories (optional). You can download databases later, see documentation for more details.

Edit H:\CBSU\updates\tasks and H:\CBSU\updates\tasks.repeat. These files define scripts that are executed on each node before BioHPC calculations start. The first script runs only once on a node, the other each time when a job starts.

Install SQLExpress Advanced, choose both modes of authentication (Windows and server) for database access.

Copy  CBSUJOBS database from installation to the local data directory of your SQL server. Attach this database.

Create an account for database access (recommended name biohpcsql) with local SQL server authorization, set password (later needed in setup.aspx).

Allow biohpcsql to write data to database and execute stored procedures newdb, newjob, newrtjob.

Install Perl.

Install Visual Studio 2005 + VS 2005 SP1 (optional). You will need Visual Studio if you want to recompile programs or interface.

Install Windows SDK and .NET 3.0 runtime

Set up IIS virtual directory (recommended name BioHPC) for BioHPC with ASP.NET and a special Application Pool running as IDU

Enable ASP .NET Web Extension in IIS

Sometimes there are problems deploying ASP.NET on the server when it is the first ASP.NET site on the server. You may need CleanIISScriptMaps.exe if there are problems with registering BioHPC with .NET 2. Check .NET registration status in "Properties" of the virtual directory.

Enable SQL Express TCP/IP channel (if using SQL Express)

Enable both authorization modes in SQL (local and Windows, parameter LoginMode 2). You will need to do it only if you forgot to select this option during installation.

Set up virtual directories JOBS (pointing to H:\CBSU\JOBS) and CBSUFTP, setup them to display various file types other than html or aspx as text (MIME: .* text/plain)

Add IDU to iis_wpg group on web serevr.

Make web.config and all other *.exe.config (JSDLupdate, rtsched, StarDaemon) files fully readable/writable by IDU

Make sure all directories in BioHPC web site are accessible to IDU

Create file H:\CBSU\BioHPC_url readable/writable to IDU with full INTERNAL (from CCS cluster) url to BioHPC web server.

Create echeck.log with full control for IDU in BioHPC web directory.

Make sure local drives T: from the nodes are exported as t-drive with full control access for IDU

Make messages subdirectory in BioHPC web directory with full control access for IDU

 On the web server, open http://localhost/BioHPC/setup.aspx and set local parameters. This file won't open outside the server.

If using SQL Express locally, the server name is server\SQLEXPRESS

Login as admin@biohpc with initial password BioHPC4All . Change initial administrator id to a valid e-mail address and change the password.

Set up ftp server for BioHPC (optional). Create JOBS and PBLAST directories at ftproot, writable to IDU locally. Create virtual directories JOBS and PBLAST readable to IDU. Export JOBS and PBLAST as UNC from the server, full access for IDU. If the FtpJobsUnc parameter in setup.aspx is empty, the it is assumed that the ftp server is not installed.

Modify acknowledgemnt.htm

Recompile ptools if necessary (present in H:\CBSU\src). Update binaries at H:\CBSU\ptools\mpims and H:\CBSU\bin_x64 using files from ptools\debug.

Set up automated tasks in Task Scheduler.

• JSDLupdate. This service is required for JSDL clusters. Add a task (as IDU) for web_dir\JSDLupdate\bin\Debug\JSDLupdate.exe, running every 3 minutes, with no timeout (i.e. 72 hrs timeout). This task may take long when downloading files from JSDL cluster, but new task won't start until the previous one finishes.

• StarDaemon. This service will update job information in BioHPC database, send required e-mail to the users without need of administrator action. Add a task (as IDU) for web_dir\StarDaemon\bin\Debug\StarDaemon.exe, running every 30 minutes, with no timeout.